Radiotherapy Alone for Primary Merkel Cell Carcinoma

Radiotherapy alone for primary Merkel cell carcinoma.

BACKGROUND Merkel cell carcinoma is a rare and potentially aggressive cancer of the skin. Cumulative data from small retrospective series have supported treatment by wide excision and adjuvant radiotherapy. However, wide excision may be difficult to perform in patients with tumors of the head and neck or in older populations with comorbidities that may be incompatible with general anesthesia. ...

Primary Cutaneous Neuroendocrine Carcinoma , Merkel Cell Carcinoma .

Merkel Cell Carcinoma: When Does Size Matter for Radiotherapy?

Merkel cell carcinoma is a very aggressive, rare cancer of the skin. It has a high propensity for local, regional, and distant recurrence and has recently been associated with a viral etiology from the recently diagnosed Merkel Cell Polyoma Virus. The optimal management remains controversial. We discuss the case of a man with a 26 cm axillary lymph node metastasis of unknown primary treated wit...

Merkel cell carcinoma and multiple primary cancers.

Merkel cell carcinoma (MCC) is an aggressive neuroendocrine tumor of the skin for which causative factors remain largely unknown. The site-specific risks of multiple primary cancers associated with MCC, which may provide insight into etiologic influences, have not been quantified in large population-based studies. We estimated the long-term risk of subsequent primary tumors after a first primar...

Prognostic Factors in Primary Merkel Cell Carcinoma

Finland Academic dissertation To be publicly discussed, with the permission of the medical Faculty of the University of This thesis is based on the following original articles, which are referred to in the text by their Roman numerals. Some unpublished data are also presented.